SMALL MOLECULES FOR BIG CLINICAL NEEDS

 

Mission Can-Fite has a mission to provide novel, effective and safe therapeutics for major clinical needs. Can-Fite develops small molecule drugs for treating autoimmune inflammatory conditions, cancer and liver diseases.
Technology Can-Fite's drug development efforts are built on a proprietary A3 adenosine receptor platform & drug discovery engine protected by strong multi-layered intellectual property
Pipeline Can-Fite has a pipeline of novel highly selective, small molecules, A3 adenosine receptor agonists, with potent activities in autoimmune inflammatory conditions, cancer and liver diseases.
Lead drug Can-Fite's lead drug – CF101 – is an oral drug with a very favorable human safety profile. CF101 is currently in Phase IIb clinical studies for the treatment of rheumatoid arthritis with demonstrated human proof-of-concept. Additional 2 Phase IIa studies in Psoriasis and Dry Eye Syndrome are currently on going.
 
Latest News Upcoming Events   Israeli office USA office

Can-Fite Successfully Completed Phase I Clinical Trial with its 2nd Drug CF102. Prepares for next phase of clinical trials in liver diseases. May 4, 2008

Can-Fite: First Patient was enrolled to the Phase IIb Rheumatoid Arthritis Trial. The study will include 230 RA patients at 30 medical sites in Europe and Israel.Rheumatoid Arthritis market is currently estimated at about $11 Billion. April 1, 2008

Can-Fite Initiated Phase I Clinical Trial with CF102. First Cohort was Successfully Completed. CF102 is indicated for the treatment of liver diseases. February 17, 2008

Can-Fite and NIH Signed a Continuation of M-CRADA to Further Investigate CF101 for the Treatment of Uveitis. The agreement was signed based on positive data generated at leading lab at the National Eye Institute (NEI) at the NIH. A successful collaboration will prompt Can-Fite to the conductance of a Phase II clinical trial to test the efficacy of CF101 in the treatment of Uveitis. Uveitis is an inflammatory disease that involves the internal parts of the eye; it affects about 1 million people worldwide and its current market is estimated at about half a billion dollars. January 16, 2008

Can-Fite Receives FDA Approval to Conduct Phase I Study with CF102. IND application submitted by Can-Fite last month was approved; phase I study will be initiated in the US in Q1 2008. The Company also received $0.5 million minimal royalty payment on CF101 from Seikagaku Corporation (SKK). January 7, 2008

more...

Can-Fite BioPharma to present at AACR Annual Meeting 2008, April 12-16, San Diego, CA, USA.
Presenting the following: CF102 an A3 adenosine receptor agonist induces in vivo apoptosis of Hepatocellular carcinoma

Can-Fite BioPharma to present at ILSI BioMed 2008. May 27-29, 2008, Tel Aviv, Israel.
Presenting the following: Can-Fite Biopharma - Small Molecules for Big Clinical Needs

 

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